With human help, the mammals can defy'the world's most fundamental natural boundaries.' Breakthroughs, discoveries, and DIY tips sent every weekday. Despite not exactly being world-renowned swimmers, pigs have spread across the Asia-Pacific region for thousands of years . With the genetic and archeological data from over 700 pigs, a team of scientists documented how people helped the mammals make their way across thousands of miles. "This research reveals what happens when people transport animals enormous distances, across one of the world's most fundamental natural boundaries," evolutionary geneticist and study co-author author Dr. David Stanton of the University of Cardiff and Queen Mary University of London said in a statement. "These movements led to pigs with a melting pot of ancestries. These patterns were technically very difficult to disentangle, but have ultimately helped us understand how and why animals came to be distributed across the Pacific islands."

Pots, quadrants, confederation constraints, group position grids... the 2026 World Cup finals draw on Friday is not going to be a straightforward affair. There's a lot to unpack so we're going to explain it as simply as we can. Luckily, Fifa will have a computer to do most of the heavy lifting and make sure everything runs smoothly. Though as Uefa found out in 2021, sometimes technology does go wrong. Let's hope there will be no gremlins in Washington once the draw ceremony kicks off.

We introduce AbBiBench (Antibody Binding Benchmarking), a benchmarking framework for antibody binding affinity maturation and design. Unlike previous strategies that evaluate antibodies in isolation, typically by comparing them to natural sequences with metrics such as amino acid recovery rate or structural RMSD, AbBiBench instead treats the antibody-antigen (Ab-Ag) complex as the fundamental unit. It evaluates an antibody design's binding potential by measuring how well a protein model scores the full Ab-Ag complex. We first curate, standardize, and share more than 184,500 experimental measurements of antibody mutants across 14 antibodies and 9 antigens-including influenza, lysozyme, HER2, VEGF, integrin, Ang2, and SARS-CoV-2-covering both heavy-chain and light-chain mutations. Using these datasets, we systematically compare 15 protein models including masked language models, autoregressive language models, inverse folding models, diffusion-based generative models, and geometric graph models by comparing the correlation between model likelihood and experimental affinity values. Additionally, to demonstrate AbBiBench's generative utility, we apply it to antibody F045-092 in order to introduce binding to influenza H1N1. We sample new antibody variants with the top-performing models, rank them by the structural integrity and biophysical properties of the Ab-Ag complex, and assess them with in vitro ELISA binding assays. Our findings show that structure-conditioned inverse folding models outperform others in both affinity correlation and generation tasks. Overall, AbBiBench provides a unified, biologically grounded evaluation framework to facilitate the development of more effective, function-aware antibody design models.

Large Language Models (LLMs) are rapidly being adopted in conservation to address the biodiversity crisis, yet their reliability for species evaluation is uncertain. This study systematically validates five leading models on 21,955 species across four core IUCN Red List assessment components: taxonomy, conservation status, distribution, and threats. A critical paradox was revealed: models excelled at taxonomic classification (94.9%) but consistently failed at conservation reasoning (27.2% for status assessment). This knowledge-reasoning gap, evident across all models, suggests inherent architectural constraints, not just data limitations. Furthermore, models exhibited systematic biases favoring charismatic vertebrates, potentially amplifying existing conservation inequities. These findings delineate clear boundaries for responsible LLM deployment: they are powerful tools for information retrieval but require human oversight for judgment-based decisions. A hybrid approach is recommended, where LLMs augment expert capacity while human experts retain sole authority over risk assessment and policy.

Trump drops bombshell Tylenol autism announcement as he vows to rip up'disgraceful' vaccine schedule in major medical shake-up Jimmy Kimmel Live! will return TOMORROW after host was canned over Charlie Kirk comments Tylenol maker responds to Trump's plans to link everyday drug to autism The six hidden messages in the texts between Charlie Kirk's'assassin' and his trans lover DECODED Top plastic surgeon reveals secrets behind Catherine Zeta-Jones' youthful appearance: 'This isn't what happens when we age' Common kitchen spice may reverse Alzheimer's disease, study suggests Barack and Michelle Obama arrive apart on Spielberg's yacht after ex-president's startling marriage confession Miley Cyrus shares the medicine that has kept her'grounded in a sober lifestyle' for 5 years Jimmy Kimmel steps in to'protect' Ivanka Trump from handsy comedian in resurfaced video Seven charities including Teenage Cancer Trust cut ties with Sarah Ferguson after leaked email showed her apologising to'supreme friend' Jeffrey Epstein Heather Locklear fans can't believe how amazing the Melrose Place vet looks at 63... 40 years after fame hit'Brazilian Josef Fritzl' makes chilling claim to police after'holding stepdaughter captive for 22 years' American'sexpert' deported from Indonesia after furious Muslim officials accused her of hosting KAMA SUTRA demonstrations Beloved actress who played loud, loving matriarch in 2002 romcom makes rare outing in LA...can you guess who? Face of man who tried to'murder Jeffrey Epstein' days before pedophile financier's mysterious suicide Candace Owens says she'll make Brigitte Macron submit to MEDICAL EXAM after'French first lady is a man' claim sparked lawsuit Blindfolded and awaiting death: Horrifying footage shows Hamas executing'Israeli collaborators' in Gaza streets as baying crowd screams'Allahu Akbar' All the'Biblical signs' pointing to the Rapture coming TOMORROW as believers spread fears the end is nigh New'loaded water' trend slashes cravings so you can lose weight... as expert reveals how to maximize benefits Clear and startling images of what appears to be a UFO were captured over Los Angeles, sparking fresh debate about what's flying over America's biggest cities. A pair of Los Angeles residents were on their balcony when they spotted a black, V-shaped craft covered in lights moving slowly over the city on August 28. The sighting went on for roughly 25 minutes, with the UFO flying south until the witnesses eventually lost sight of it around 11:38pm local time (2:38am ET). The pair was able to capture both pictures and clear videos with a cellphone camera, zooming in to see nine white lights along the UFO's hull.

"The males lost all their energy and lay immobile on the bottom while the female swam away actively." Breakthroughs, discoveries, and DIY tips sent every weekday. Marine biologists recently documented a promising (if intimate) marine moment in the ocean waters near northeast Australia. For the first time, researchers recorded a leopard shark () mating event. But the footage doesn't showcase a pair of the endangered predators going at it--the brief tryst involved three participants.

Gabrielle surging into major hurricane as forecasters warn of'life-threatening' impact to East Coast Fed governor installed by Trump outlines bold case to slash interest rates to 2.5% in months So is Meghan Markle's former best pal about to tell all? Jessica Mulroney has an axe to grind and'knows where the bodies are buried', friends warn amid claims she's penning memoir Incredible secret DNA weapon that nailed Bryan Kohberger... and how no criminal can hide again Why Jennifer Aniston is'being silenced' from speaking out on close friend Jimmy Kimmel's firing Six charities including Teenage Cancer Trust cut ties with Sarah Ferguson after leaked email showed her apologising to'supreme friend' Jeffrey Epstein Will Smith's'nepo baby' son Jaden sparks outrage after landing coveted job at designer fashion brand I've had crippling anxiety for years. Heather Locklear fans can't believe how amazing the Melrose Place vet looks at 63... 40 years after fame hit Whoopi Goldberg claims The View is too fearless not to discuss Kimmel canning... despite completely avoiding subject at crucial moment There's a new dating trend that's great news for guys who struggle to get laid. Even divorce lawyers say it's the secret to happiness. But ladies, I promise it'll backfire I'm a 49-year-old beauty editor and menopause gave me hair loss and short, brittle locks that wouldn't grow.

This paper introduces SpaPool, a novel pooling method that combines the strengths of both dense and sparse techniques for a graph neural network. SpaPool groups vertices into an adaptive number of clusters, leveraging the benefits of both dense and sparse approaches. It aims to maintain the structural integrity of the graph while reducing its size efficiently. Experimental results on several datasets demonstrate that SpaPool achieves competitive performance compared to existing pooling techniques and excels particularly on small-scale graphs. This makes SpaPool a promising method for applications requiring efficient and effective graph processing.